ABSTRACT
ABSTRACT Objective To evaluate the effect of the COVID-19 impacts on the activities of researchers in the field of Oral Medicine (OM) and Oral Pathology (OP). To assess the research activities and training of human resources by Brazilian productivity fellows in research (BPFR) in OM and OP in the COVID-19 Era. Material and Methods Thirty-six BPFR in OM and OP areas, funded by National Council for Scientific and Technological Development (CNPq), received a virtual structured questionnaire by e-mail, on the Google Forms (Google®) platform, with questions regarding research activities and training of human resources (supervision of undergraduate and postgraduate students), during the COVID-19 pandemic. From the thirty-six BPFR in OM and OP, twenty-seven (75.0%) answered the questionnaire. Results Most of them were males (n=20; 74.1%) and were distributed in four Brazilian regions and ten states of the federation, including the Federal District. Twenty-four (88.9%) BPFR reported having suspended clinical activities, while sixteen (59.3%) answered that histopathology practices are suspended. Twenty-five (92.6%) BPFR mentioned difficulties in conducting research projects and 55.5% stated having no difficulties in the supervision of undergraduates, master's and PhD students. Conclusion The current scenario may significantly impact the diagnosis of oral diseases in Brazil. Moreover, a decrease in the scientific production of BPFR in OM and OP in the coming years is also considered.
Subject(s)
Humans , Male , Female , Pathology, Oral , Research Support as Topic , Training Support , Brazil/epidemiology , Oral Medicine , COVID-19 , Research , Technological Development , Surveys and Questionnaires , Data Interpretation, Statistical , Workforce , MentoringABSTRACT
Objetivo: Realizar um levantamento epidemiológico de todos os casos de tumores de glândulas salivares diagnosticados em um Laboratório de Histopatologia Oral. Métodos: Descrição da amostra e avaliação de fichas clínicas de todos os pacientes que deram entrada com pedido de solicitação de exame histopatológico no referido laboratório, no período compreendido entre janeiro de 2001 e janeiro de 2015. Resultados: Cinquenta casos foram encontrados, dos quais 68,7% eram benignos. Houve predominância no sexo feminino (68%). A faixa etária mais frequente foi de 41 a 60 anos (40%). A maioria dos casos ocorreu nas glândulas salivares menores (70,0%), sendo o palato duro o local mais frequente (38%). Para a coleta do espécime e envio ao laboratório, a biópsia excisional foi o método de eleição (46%), sendo o adenoma pleomórfico a neoplasia mais comum (62,0%). Conclusões: Os tumores de glândulas salivares afetam mais mulheres na faixa etária entre 41 e 60 anos. Atenção especial deve ser dada aos nódulos submucosos palatinos, devido à alta prevalência de tumores malignos nas glândulas salivares menores.
Objective: To perform an epidemiological study of all cases of salivary gland tumors diagnosed in an Oral Pathology Laboratory. Methods: Sample description and evaluation of medical records of all patients who were admitted for histopathological examination request in the above-mentioned Laboratory, from January 2001 and January 2015. Results: Fifty cases were found, 68.7 % were benign. Most patients were from female gender (68,0 %). The most common age group was 41-60 years (40,0%). Most cases affected minor salivary glands (70.0 % ), mainly the hard palate (38,0 %). To obtain the specimen and sent for histopathological analysis, the excisional biopsy was the method of choice (46,0 %), and the pleomorphic adenoma was the most common diagnosis (62,0 %). Conclusions: Salivary gland tumors affect more commonly women aged between 41-60 years. The practitioners should pay special attention to palatine submucous nodules, owing the high prevalence of malignant tumors in minor salivary glands.
ABSTRACT
O presente estudo avaliou a atividade antiinflamatória de antiinflamatórios não-esteroidais (AINEs)em tecido pulpar de ratos, por meio de microscopia óptica. Preparos cavitários foram realizados nos incisivossuperiores de 40 ratos para a indução de processo inflamatório pulpar. Os animais foram distribuídos aleatoriamenteem 5 grupos segundo a medicação administrada: G1 - celecoxib; G2 - rofecoxib; G3 - diclofenacode sódio; G4 - ibuprofeno e G5 - solução fisiológica (controle). A terapia com AINEs foi iniciada apo?s 24 horasda realização da exposição pulpar. Nos períodos de 1, 3, 5 e 7 dias após o início da terapia medicamentosa,2 animais de cada grupo foram sacrificados e tiveram seus dentes extraídos para a análise histológica dotecido pulpar. Os índices utilizados para avaliação qualitativa variaram de 1 (tecido quase regenerado) até6 (inflamação severa). Os dados foram analisados por meio de Análise de Variância e teste de Tukey. Verificou-se que todos os medicamentos testados foram capazes de reduzir a inflamação quando comparadosao grupo controle. O grupo tratado com celecoxib apresentou os melhores resultados na redução do quadroinflamatório (p<0,01), seguido pelo rofecoxib e ibuprofeno, que se comportaram de maneira estatisticamentesemelhantes entre si (p>0,01) e superiores ao diclofenaco de sódio (p<0,01).
This study evaluated the anti-inflammatory effect of non-steroids anti-inflammatory (AINEs) in rat´s pulps,behind optic microscopy. Cavities were done in maxillary incisors of 40 rats to induce pulp inflammatory.The animals were divided in 5 groups according to medication: G1 - celecoxib; G2 - rofecoxib; G3 - diclofenacode sódio; G4 - ibuprofeno and G5 - saline (control). The therapy was initialized 24 hours after the pulpexposition. In the periods of 1, 3, 5 and 7 days after the therapy, 2 animals of each group were sacrificedand had their teeth extracted to histological analysis of pulp tissue. The scores were 1 (healed tissue) to 6(severe inflammation). The data were evaluated by Variance analysis and Tukey´s test. It was verified thatall medicaments were capable to reduce inflammation compared to control group. The celecoxib group presentedthe best results in reduction of inflammation (p<0,01), followed by rofecoxib and ibuprofeno, whichwere statistically equal (p>0,01) and better than diclofenaco de sódio (p<0,01).